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  • Patrick G Johnston Centre for Cancer Research
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  • Meet our Researchers
  • Find a PhD Supervisor

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Find a PhD Supervisor

Dr Simon McDade

School of Medicine, Dentistry and Biomedical Sciences
Simon McDade

Dr Simon McDade

School of Medicine, Dentistry and Biomedical Sciences

The Functional Genomics Group focusses on the use of cutting-edge genomics technologies to investigate transcription factor function and de-regulation in cancer with a particular interest in the p53 family.

We believe that a better understanding of the genome-wide targets, mechanism of action and consequences of de-regulation of key transcription factors; will allow us to identify cancer specific dependencies, that represent “Achilles heels”, exploitable with novel treatment strategies to improve patient outcomes.

Contact info

  • askmhls@qub.ac.uk
  • +44 (0)28 9097 2183

Research Interests

Open to PhD applications in the field of

  • Transcription dysfunction in disease
  • Functional genomics and integrative bioinformatics
  • Identification of novel genomically informed treatment strategies

Make a PhD enquiry


Current Research Opportunities

  • Using epigenetic modifiers in combination with 5-FU based chemotherapy to elicit tumour specific immune responses and immunogenic cell death in colorectal cancer.
  • Novel approaches to uncovering effects of anti-cancer agents targeting epigenetic modifiers.
  • Using epigenetic modifiers in combination with 5-FU based chemotherapy to elicit tumour specific immune responses and immunogenic cell death in colorectal cancer.
  • Novel approaches to uncovering effects of anti-cancer agents targeting epigenetic modifiers.

Public outreach & key achievements

  • Academic Lead FMHLS Genomics Core Technology Unit
  • Co-Investigator on  funded by Bobby Moore Foundation
  • Co-Investigator 
  • Pre-Clinical Lead CRUK 

 


Discover More

  • Faculty of Medicine, Health and Life Sciences

  • Gastro-Intestinal Focus Group

Postgraduate research
Your postgraduate experience
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School of Medicine, Dentistry and Biomedical Sciences

Whitla Medical Building,
97 Lisburn Road,
Belfast, BT9 7BL

Phone: +44 (0)2890 972215

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